Test Results For:
Coombs Direct Test (Direct Antiglobulin Test - Dat)
Test Overview
Test Name
Coombs Direct Test (Direct Antiglobulin Test - Dat)
Test Code
COOMBS
Short Description
COOMBS
Test Name
Coombs Direct Test (Direct Antiglobulin Test - Dat)
Test Code
COOMBS
Category
Immunohaematology
TAT
Main Lab:
6
Hour(s)
Family Site:
<8hrs
Specimen(s)
1 x Venous blood - 5 mL Tube - Lavender - EDTA Plasma
Specimen Type
EDTA Plasma
Specimen Format
Tube
Specimen Colour
Lavender
Specimen Volume
5 mL
Sampling Order
4
Origin
Venous blood
Collection Time after baseline
-
Transport Temperature
15-25°C
Accepted Other Specimens
-
TAT
Main Lab:
6
Hour(s)
Family Site:
<8hrs
Test Stability
Room Temp:
24 Hour(s)
2–8°C:
72 Hour(s)
Methodology
Hemagglutination
Specimen Type
EDTA Plasma
Delay before pre-treatment
-
Transport temperature
15-25°C
Test stability at room temperature
24 Hour(s)
Test stability at 2–8°C
72 Hour(s)
Haemolysis interference
No
Clinical Interest
The direct coombs test is a biological examination used to look for antibodies or complement proteins that have attached themselves to the surface of red blood cells (RBCs). This test is used to diagnose various pathologies that cause haemolytic anaemia, a disease in which red blood cells are destroyed faster than the body can replace them.
The direct coombs test is used to investigate a number of conditions:
- Autoimmune haemolytic anaemia (AIHA): this is a condition in which the body's immune system attacks its own red blood cells.
- Drug-induced haemolytic anaemia: Certain drugs can cause the body to produce antibodies that attack red blood cells. The direct coombs test may be positive in these cases.
- Haemolytic disease of the newborn (HDN): This disease occurs when the mother's antibodies attack the baby's red blood cells. The direct coombs test is positive in most cases of HDN.
Clinical Information Required
-
Patient Collection Note
-
LOINC Code
04-1, 1004-1
Outwork
No