This bilirubin has been processed by the liver and conjugated with glucuronic acid, making it water-soluble. Elevated conjugated bilirubin levels can indicate liver dysfunction, where the liver cannot process and excrete bilirubin effectively.

Conditions such as hepatitis, cirrhosis, and liver cancer may be implicated. Conditions like cholestasis, where there is an impairment in the flow of bile from the liver, lead to an accumulation of conjugated bilirubin in the blood.

This can occur due to bile duct obstructions, such as gallstones or strictures.

• Mild Elevation: This can be seen in conditions such as Gilbert's syndrome or if mild hepatic impairment.
• Moderate to Severe Elevation: Suggestive of more serious liver dysfunction, cholestasis, or bile duct obstruction.